Functional Regulation of Dopamine D3Receptor through Interaction with PICK1
نویسندگان
چکیده
منابع مشابه
Functional Regulation of Dopamine D3 Receptor through Interaction with PICK1
PICK1, a PDZ domain-containing protein, is known to increase the reuptake activities of dopamine transporters by increasing their expressions on the cell surface. Here, we report a direct and functional interaction between PICK1 and dopamine D₃ receptors (D₃R), which act as autoreceptors to negatively regulate dopaminergic neurons. PICK1 colocalized with both dopamine D₂ receptor (D₂R) and D₃R ...
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ژورنال
عنوان ژورنال: Biomolecules & Therapeutics
سال: 2016
ISSN: 2005-4483,1976-9148
DOI: 10.4062/biomolther.2016.015